Just to be clear, there is no CAM5 in CCSM. CAM5 is only in the CESM.
Running CAM in a "standalone" mode is somewhat ambiguous.
The CAM standalone configuration, i.e., CAM with a data ocean (docn), active land (clm), and a thermodynamic sea ice component (cice), can be run using the CESM scripts, or using CAM standalone scripts. Running with the CESM scripts is the recommended way since these scripts provide a lot of support for doing production runs. To run CAM standalone from the CESM scripts you just specify one of the "F" compsets to the create_newcase command.
CAM standalone scripts (there are some example standalone scripts in models/atm/cam/bld/) require a more expert level of knowledge. They are only capable of running CAM in the standalone configuration, and are most suitable for development work rather than production runs.
The only difference between running the CAM standalone configuration from the CESM scripts versus from the CAM standalone scripts is the scripts themselves. The driver code and all components are identical regardless of the scripts used to build the model.